Lowe Syndrome also known as Oculocerebrorenal Syndrome is a rare genetic disorder that affects the eyes, brain and kidneys. It has a prevalence of 1 in 500,000 and mainly affects males.
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Signs and Symptoms
- Congenital cataracts
- eye abnormalities and eye disease
- glaucoma
- kidney abnormalities (Renal Fanconi Syndrome)
- dehydration
- abnormal acidic blood
- progressive kidney problems
- feeding problems
- bone abnormalities
- scoliosis
- weak or low muscle tone (hypotonia)
- joint problems
- developmental delays including motor skills
- short stature
- intellectual disability
- seizure
- behavioral issues
Children and adults diagnosed with children and adults may also show the following signs and symptoms due to an intellectual disability:
- decrease learning ability
- delays in crawling
- delays in sitting up
- difficulty solving problems
- lack of curiosity
- language and speech delays
- poor memory
- behavior problems
Teaching Strategies
The following strategies will help when teaching a child or an adult diagnosed with Lowe Syndrome:
- Use short and simple sentences to ensure understanding
- Repeat directions
- Teach specific skills when possible
- Use strategies such as chunking, backwards shaping, forward shaping and role modeling.
- Use concrete information
- Provide immediate feedback
Image thanks to Robert Thomson on Flickr.com (creative commons)